Examples

"But I am looking forward to the double-blind placebo-controlled trials," he says.

Much of the clinical data supporting CES devices is outdated; a few small placebo-controlled trials of the Fisher Wallace device are planned at Harvard, Columbia and the University of Toledo.

The treatment was being studied in a randomized, placebo-controlled phase III trial called Study 14, evaluating Zibotentan at a dosage of 10 milligrams that was added to standard of care treatment in 594 patients having metastatic castration resistant prostate cancer, or CRPC.

Dr. Hartwell, who wasn't involved in the study, said social-network trials aren't likely to replace conventional randomized, double-blinded, placebo-controlled trials, the gold-standard for generating medical evidence.

The randomized, placebo-controlled trial, called FEM-PrEP, was carried out among 1,951 women in South Africa, Kenya, and Tanzania by FHI, a non-profit health and development organization, with about $23 million in funding from the United States Agency for International Development and about $3 million from the Bill and Melinda Gates Foundation.

The authors and several of the medical experts they interviewed seem to imply that the vaccines have not undergone rigorous efficacy tests of any kind, yet a cursory look at the relevant medical literature reveals a number of peer-reviewed papers that certainly appear to be evaluations of vaccine efficacy using a randomized, placebo-controlled design.

A much larger (n = 294) randomized, prospective, double-blind, placebo-controlled study (EMPOWER) is currently being conducted in the United States and Australia is expected to report in the second half of this year.

Snitker et al. conducted a 12-wk, placebo-controlled. double-blind, randomized study of oral capsinoids (6 mg/d) in 40 men and 40 women.

Dr. Chen said larger, randomized placebo-controlled studies are needed to confirm the results.

Because I've looked through all the randomized, double-blind, placebo-controlled clinical trials that have ever been conducted on H1N1 vaccines.