This was a randomised, double-blind placebo-controlled trial. The researchers said that cytisine has been available in Bulgaria since 1964 and is commercially available in countries such as Poland and Russia for approximately US $6-$15 per course of treatment. However, they said that despite the drug’s widespread use there have not yet been any large placebo-controlled trials that would adhere to modern regulatory standards. This study was performed to fulfil this requirement.
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